Network context and selection in the evolution to enzyme specificity. |
H. Nam; N.E. Lewis; J.A. Lerman; D.H. Lee; R.L. Chang; D. Kim; B.O. Palsson |
2012 |
Predicting outcomes of steady-state ¹³C isotope tracing experiments using Monte Carlo sampling. |
J. Schellenberger; D.C. Zielinski; W. Choi; S. Madireddi; V. Portnoy; D.A. Scott; J.L. Reed; A.L. Osterman; B. Palsson |
2012 |
Comparative Analysis of Regulatory Elements between Escherichia coli and Klebsiella pneumoniae by Genome-Wide Transcription Start Site Profiling. |
D. Kim; J.S.J. Hong; Y. Qiu; H. Nagarajan; J.H. Seo; B.K. Cho; S.F. Tsai; B.Ø. Palsson |
2012 |
Model-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation. |
A. Bordbar; M.L. Mo; E.S. Nakayasu; A.C. Schrimpe-Rutledge; Y.M. Kim; T.O. Metz; M.B. Jones; B.C. Frank; R.D. Smith; S.N. Peterson; D.R. Hyduke; J.N. Adkins; B.O. Palsson |
2012 |
Maximizing biomass productivity and cell density of Chlorella vulgaris by using light-emitting diode-based photobioreactor. |
W. Fu; O. Gudmundsson; A.M. Feist; G. Herjolfsson; S. Brynjolfsson; B.O. Palsson |
2012 |
Intracellular metabolite profiling of platelets: evaluation of extraction processes and chromatographic strategies. |
G. Paglia; M. Magnúsdóttir; S. Thorlacius; O.E. Sigurjónsson; S. Guðmundsson; B.Ø. Palsson; I. Thiele |
2012 |
A variational principle for computing nonequilibrium fluxes and potentials in genome-scale biochemical networks. |
R.M.T. Fleming; C.M. Maes; M.A. Saunders; Y. Ye; B.Ø. Palsson |
2012 |
In silico method for modelling metabolism and gene product expression at genome scale |
J.A. Lerman; D.R. Hyduke; H. Latif; V.A. Portnoy; N.E. Lewis; J.D. Orth; A.C. Schrimpe-Rutledge; R.D. Smith; J.N. Adkins; K. Zengler; B.O. Palsson |
2012 |
Gap-filling analysis of the iJO1366 Escherichia coli metabolic network reconstruction for discovery of metabolic functions. |
J.D. Orth; B.O. Palsson |
2012 |
Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction. |
P. Charusanti; N.L. Fong; H. Nagarajan; A.R. Pereira; H.J. Li; E.A. Abate; Y. Su; W.H. Gerwick; B.O. Palsson |
2012 |
Systems biology of stored blood cells: can it help to extend the expiration date? |
G. Paglia; B.Ø. Palsson; O.E. Sigurjonsson |
2012 |
Detailing the optimality of photosynthesis in cyanobacteria through systems biology analysis. |
J. Nogales; S. Gudmundsson; E.M. Knight; B.O. Palsson; I. Thiele |
2012 |
Proteomic analysis of Chinese hamster ovary cells. |
D. Baycin-Hizal; D.L. Tabb; R. Chaerkady; L. Chen; N.E. Lewis; H. Nagarajan; V. Sarkaria; A. Kumar; D. Wolozny; J. Colao; E. Jacobson; Y. Tian; R.N. O'Meally; S.S. Krag; R.N. Cole; B.O. Palsson; H. Zhang; M. Betenbaugh |
2012 |
Constraining the metabolic genotype-phenotype relationship using a phylogeny of in silico methods. |
N.E. Lewis; H. Nagarajan; B.O. Palsson |
2012 |
Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS). |
G. Paglia; S. Hrafnsdóttir; M. Magnúsdóttir; R.M.T. Fleming; S. Thorlacius; B.Ø. Palsson; I. Thiele |
2012 |
MODELING HOST-PATHOGEN INTERACTIONS: COMPUTATIONAL BIOLOGY AND BIOINFORMATICS FOR INFECTIOUS DISEASE RESEARCH. |
J.E. McDermott; P. Braun; R. Bonneau; D.R. Hyduke |
2012 |
Anaerobic utilization of toluene by marine alpha- and gammaproteobacteria reducing nitrate. |
K. Alain; J. Harder; F. Widdel; K. Zengler |
2012 |
Using the reconstructed genome-scale human metabolic network to study physiology and pathology. |
A. Bordbar; B.O. Palsson |
2012 |
Sensitive and accurate identification of protein-DNA binding events in ChIP-chip assays using higher order derivative analysis. |
C.L. Barrett; B.K. Cho; B.O. Palsson |
2011 |
An experimentally validated genome-scale metabolic reconstruction of Klebsiella pneumoniae MGH 78578, iYL1228. |
Y.C. Liao; T.W. Huang; F.C. Chen; P. Charusanti; J.S.J. Hong; H.Y. Chang; S.F. Tsai; B.O. Palsson; C.A. Hsiung |
2011 |
Functional and metabolic effects of adaptive glycerol kinase (GLPK) mutants in Escherichia coli. |
K.M. Applebee; A.R. Joyce; T.M. Conrad; D.W. Pettigrew; B.Ø. Palsson |
2011 |
The role of cellular objectives and selective pressures in metabolic pathway evolution. |
H. Nam; T.M. Conrad; N.E. Lewis |
2011 |
The PurR regulon in Escherichia coli K-12 MG1655. |
B.K. Cho; S.A. Federowicz; M. Embree; Y.S. Park; D. Kim; B.Ø. Palsson |
2011 |
Adaptive Laboratory Evolution |
B.Ø. Palsson |
2011 |
Adaptive laboratory evolution--harnessing the power of biology for metabolic engineering. |
V.A. Portnoy; D. Bezdan; K. Zengler |
2011 |
In situ to in silico and back: elucidating the physiology and ecology of Geobacter spp. using genome-scale modelling. |
R. Mahadevan; B.Ø. Palsson; D.R. Lovley |
2011 |
The human metabolic reconstruction Recon 1 directs hypotheses of novel human metabolic functions. |
O. Rolfsson; B.Ø. Palsson; I. Thiele |
2011 |
A c-type cytochrome and a transcriptional regulator responsible for enhanced extracellular electron transfer in Geobacter sulfurreducens revealed by adaptive evolution. |
P.L. Tremblay; Z.M. Summers; R.H. Glaven; K.P. Nevin; K. Zengler; C.L. Barrett; Y. Qiu; B.O. Palsson; D.R. Lovley |
2011 |
Microbial laboratory evolution in the era of genome-scale science. |
T.M. Conrad; N.E. Lewis; B.Ø. Palsson |
2011 |
An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92. |
P. Charusanti; S. Chauhan; K. McAteer; J.A. Lerman; D.R. Hyduke; V.L. Motin; C. Ansong; J.N. Adkins; B.O. Palsson |
2011 |