Tuberculosis - Mycobacterium tuberculosis

M.tb iNJ661

Neema Jamshidi, Bernhard Ø. Palsson Investigating the Metabolic Capabilities of Mycobacterium tuberculosis H37Rv Using the in silico Strain iNJ661 and Proposing Alternative Drug Targets BMC Systems Biology 2007, 1 :26 (8 June 2007)

• Model in SBML format

  • Growth on Middlebrook media

• Reconstruction content in Excel format

• Network maps

  • The complete network (svg format) (jpg format)

  • The complete network with Hard-Coupled Reaction Sets (svg format)

  • The drug target Hard-Coupled Reaction Sets mapped to the network (pdf)

  • Amino Acid Metabolism (svg format) (jpg format)

  • Central Metabolism (svg format) (jpg format)

  • Fatty Acid Metabolism (svg format) (jpg format)

  • Membrane Metabolism (svg format) (jpg format)

  • Nucleotide Metabolism (svg format) (jpg format)

  • Peptidoglycan Metabolism (svg format) (jpg format)

  • Transporters (svg format) (jpg format)

  • Vitamin and Cofactor Metabolism (svg format) (jpg format)

Additional Resources

• COBRA Toolbox

• Tuberculist Web Server

If you have any questions about computational modeling of tuberculosis, please email us at neema@ucsd.edu