Yeast - Saccharomyces cerevisiae

S.cerevisiae iMM904

Mo, M.L., Palsson, B.O., Herrgard, M.J., Connecting extracellular metabolomic profiles to intracellular metabolic states in yeast. BMC Systems Biology. 3:37 (2009)

Herrgard MJ, Swainston N, Dobson P, Dunn WB, Arga KY, Arvas M, Bluthgen N, Borger S, Costenoble R, Heinemann M et al. "A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology." Nat Biotech, 26: 1155-1160 (2008).

S.cerevisiae iMH805/775

Herrgard, M.J., Lee, B.-S., Portnoy, V., and Palsson, B.O. "Integrated analysis of regulatory and metabolic networks reveals novel regulatory mechanisms in Saccharomyces cerevisiae." Genome Research, 2006.

Nutrient controlled transcriptional regulatory network regulating metabolism. The network can be interfaced with the iND750 metabolic network. iMH805/775 includes 55 transcription factors, 82 nutrient signals, and 775 regulatory interactions collected from the primary literature. iMH805/837 includes additional interactions introduced into the model based on integrative analysis of high-throughput datasets.

  • iMH805/775 regulatory network: .xls

  • iMH805/837 regulatory network: .xls

  • Changes between the two networks: .xls

S.cerevisiae iND750

Duarte, N.C., Herrgard, M.J., and Palsson, B.O. "Reconstruction and Validation of Saccharomyces cerevisiae iND750, a Fully Compartmentalized Genome-scale Metabolic Model" Genome Research, 2004.

S.cerevisiae iFF708

Forster, J., Famili, I., Fu, P., Palsson, B.O., and Nielsen, J. "Genome-scale Reconstruction of the Saccharomyces cerevisiae Metabolic Network" Genome Research, 2003.