Publication Title Authors Publication Year Sort ascending
Elucidating the Regulatory Elements for Transcription Termination and Posttranscriptional Processing in the Streptomyces clavuligerus Genome.

Hwang S, Lee N, Choe D, Lee Y, Kim W, Jeong Y, Cho S, Palsson BO, Cho BK

2021
Re-classification of Streptomyces venezuelae strains and mining secondary metabolite biosynthetic gene clusters

Lee N, Choi M, Kim W, Hwang S, Lee Y, Kim JH, Kim G, Kim H, Cho S, Kim SC, Palsson B, Jang KS, Cho BK

2021
The quantitative metabolome is shaped by abiotic constraints

Akbari A, Yurkovich JT, Zielinski DC, Palsson BO

2021
Streptomyces as Microbial Chassis for Heterologous Protein Expression

Hwang S, Lee Y, Kim JH, Kim G, Kim H, Kim W, Cho S, Palsson BO, Cho BK

2021
Environmental conditions dictate differential evolution of vancomycin resistance in Staphylococcus aureus

Machado H, Seif Y, Sakoulas G, Olson CA, Hefner Y, Anand A, Jones YZ, Szubin R, Palsson BO, Nizet V, Feist AM

2021
Computation of condition-dependent proteome allocation reveals variability in the macro and micro nutrient requirements for growth

Lloyd CJ, Monk J, Yang L, Ebrahim A, Palsson BO

2021
An atlas of human metabolism

Robinson JL, Kocabaş P, Wang H, Cholley PE, Cook D, Nilsson A, Anton M, Ferreira R, Domenzain I, Billa V, Limeta A, Hedin A, Gustafsson J, Kerkhoven EJ,  Svensson LT, Palsson BO, Mardinoglu A, Hansson L, Uhlén M, Nielsen J.

2020
Impact of insertion sequences on convergent evolution of Shigella species

Hawkey J, Monk JM, Billman-Jacobe H, Palsson B, Holt KE

2020
Machine learning uncovers independently regulated modules in the Bacillus subtilis transcriptome

Rychel, K., Sastry, A.V. & Palsson, B.O.

2020
Reconstruction and Validation of a Genome-Scale Metabolic Model of Streptococcus oralis (iCJ415), a Human Commensal and Opportunistic Pathogen

Jensen CS, Norsigian CJ, Fang X, Nielsen XC, Christensen JJ, Palsson BO, Monk JM. 

2020
Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity

Phaneuf PV, Yurkovich JT, Heckmann D, et al.

2020
The Expanding Computational Toolbox for Engineering Microbial Phenotypes at the Genome Scale

Zielinski, D.C.; Patel, A.; Palsson, B.O. 

2020
Comparison of metal-bound and unbound structures of aminopeptidase B proteins from Escherichia coli and Yersinia pestis

Minasov G, Lam MR, Rosas Lemus M, Sławek J, Woinska M, Shabalin IG, Shuvalova  L, Palsson BØ, Godzik A, Minor W, Satchell KJF

2020
Synthetic cross-phyla gene replacement and evolutionary assimilation of major enzymes

Sandberg TE, Szubin R, Phaneuf PV, Palsson BO

2020
DeepTFactor: A deep learning-based tool for the prediction of transcription factors

Kim, G.B., Gao, Y., Palsson, B.O., Lee, S.Y.

2020
Genome Sequence Comparison of Staphylococcus aureus TX0117 and a Beta-Lactamase-Cured Derivative Shows Increased Cationic Peptide Resistance Accompanying Mutations in relA and mnaA

Sales MJ, Sakoulas G, Szubin R, Palsson B, Arias C, Singh KV, Murray BE, Monk JM

2020
System-level understanding of gene expression and regulation for engineering secondary metabolite production in Streptomyces

Lee Y, Lee N, Hwang S, et al.

2020
A biochemically-interpretable machine learning classifier for microbial GWAS

Kavvas ES, Yang L, Monk JM, Heckmann D, Palsson BO

2020
SBML Level 3: an extensible format for the exchange and reuse of biological models

Keating SM, Waltemath D, König M, et al.

2020
Transcriptome and translatome profiles of Streptomyces species in different growth phases.

Kim W, Hwang S, Lee N, Lee Y, Cho S, Palsson B, Cho BK.

2020
Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers

Heckmann D, Campeau A, Lloyd CJ, et al.

2020
Repurposing Modular Polyketide Synthases and Non-ribosomal Peptide Synthetases for Novel Chemical Biosynthesis

Hwang S, Lee N, Cho S, Palsson B, Cho BK
 

2020
Reconstructing organisms in silico: genome-scale models and their emerging applications

Fang X, Lloyd CJ, Palsson BO

2020
Iron competition triggers antibiotic biosynthesis in Streptomyces coelicolor during coculture with Myxococcus xanthus

Lee N, Kim W, Chung J, Lee Y, Cho S, Jang KS, Kim SC, Palsson B, Cho BK

2020
Multiplex secretome engineering enhances recombinant protein production and purity

Kol S, Ley D, Wulff T, et al.

2020
The Bitome: digitized genomic features reveal fundamental genome organization

Lamoureux CR, Choudhary KS, King ZA, Sandberg TE, Gao Y, Sastry AV, Phaneuf PV, Choe D, Cho BK, Palsson BO.

2020
Thirty complete Streptomyces genome sequences for mining novel secondary metabolite biosynthetic gene clusters

Lee N, Kim W, Hwang S, Lee Y, Cho S, Palsson B, Cho BK

2020
Adaptations of Escherichia Coli Strains to Oxidative Stress Are Reflected in Properties of Their Structural Proteomes

Mih N, Monk JM, Fang X, et al.

2020
Generation of ionic liquid tolerant Pseudomonas putida KT2440 strains via adaptive laboratory evolution

Lim, H.G., Fong, B., Alacon, G., Magrudeniya, H.D., Eng, T., Szubin, R., Olson, C.A., Palsson, B.O., Gladden, J.M., Simmons, B.A., Mukhopadhyay, Singer, S.W., Feist, A.M., 

2020
Machine learning with random subspace ensembles identifies antimicrobial resistance determinants from pan-genomes of three pathogens

Hyun JC, Kavvas ES, Monk JM, Palsson BO

2020