Publication Title Authors Publication Year Sort ascending
Thirty complete Streptomyces genome sequences for mining novel secondary metabolite biosynthetic gene clusters

Lee N, Kim W, Hwang S, Lee Y, Cho S, Palsson B, Cho BK

2020
Adaptations of Escherichia Coli Strains to Oxidative Stress Are Reflected in Properties of Their Structural Proteomes

Mih N, Monk JM, Fang X, et al.

2020
Generation of ionic liquid tolerant Pseudomonas putida KT2440 strains via adaptive laboratory evolution

Lim, H.G., Fong, B., Alacon, G., Magrudeniya, H.D., Eng, T., Szubin, R., Olson, C.A., Palsson, B.O., Gladden, J.M., Simmons, B.A., Mukhopadhyay, Singer, S.W., Feist, A.M., 

2020
Machine learning with random subspace ensembles identifies antimicrobial resistance determinants from pan-genomes of three pathogens

Hyun JC, Kavvas ES, Monk JM, Palsson BO

2020
Microbial Synthesis of Human-Hormone Melatonin at Gram Scales

Luo H, Schneider K, Christensen U, Lei Y, Herrgard M, Palsson BØ

2020
Gastrointestinal Surgery for Inflammatory Bowel Disease Persistently Lowers Microbiome and Metabolome Diversity

Fang X, Vázquez-Baeza Y, Elijah E, Vargas F, Ackermann G, Humphrey G, Lau R, Weldon KC, Sanders JG, Panitchpakdi M, Carpenter C, Jarmusch AK, Neill J, Miralles A, Dulai P, Singh S, Tsai M, Swafford AD, Smarr L, Boyle DL, Palsson BO, Chang JT, Dorrestein PC, Sandborn WJ, Knight R, Boland BS.

2020
Metabolic and genetic basis for auxotrophies in Gram-negative species

Seif Y, Choudhary KS, Hefner Y, Anand A, Yang L, Palsson BO

2020
Comparative Genomics Determines Strain-Dependent Secondary Metabolite Production in Streptomyces venezuelae Strains

Kim W, Lee N, Hwang S, et al.

2020
Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi

Shiratsubaki IS, Fang X, Souza ROO, Palsson BO, Silber AM, Siqueira-Neto JL.

2020
MEMOTE for standardized genome-scale metabolic model testing

Lieven C, Beber ME, Olivier BG, Bergmann FT, Ataman M, Babaei P, Bartell JA, Blank LM, Chauhan S, Correia K, Diener C, Dräger A, Ebert BE, Edirisinghe JN, Faria JP, Feist AM, Fengos G, Fleming RMT, García-Jiménez B, Hatzimanikatis V, van Helvoirt W, Henry CS, Hermjakob H, Herrgård MJ, Kaafarani A, Kim HU, King Z,  Klamt S, Klipp E, Koehorst JJ, König M, Lakshmanan M, Lee DY, Lee SY, Lee S, Lewis NE, Liu F, Ma H, Machado D, Mahadevan R, Maia P, Mardinoglu A, Medlock GL,  Monk JM, Nielsen J, Nielsen LK, Nogales J, Nookaew I, Palsson BO, Papin JA, Patil KR, Poolman M, Price ND, Resendis-Antonio O, Richelle A, Rocha I, Sánchez BJ, Schaap PJ, Malik Sheriff RS, Shoaie S, Sonnenschein N, Teusink B, Vilaça P, Vik JO, Wodke JAH, Xavier JC, Yuan Q, Zakhartsev M, Zhang C.

2020
Revealing 29 sets of independently modulated genes in Staphylococcus aureus, their regulators, and role in key physiological response

Poudel S, Tsunemoto H, Seif Y, et al.

2020
Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic divergence

Norsigian, C.J., Danhof, H.A., Brand, C.K. et al.

2020
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

Gutierrez JM, Feizi A, Li S, Kallehauge TB, Hefzi H, Grav LM, Ley D, Baycin Hizal D, Betenbaugh MJ, Voldborg B, Faustrup Kildegaard H, Min Lee G, Palsson BO, Nielsen J, Lewis NE

2020
Synthesizing Systems Biology Knowledge from Omics Using Genome-Scale Models

Dahal S, Yurkovich JT, Xu H, Palsson BO

2020
iModulonDB: a knowledgebase of microbial transcriptional regulation derived from machine learning

Rychel K, Decker K, Sastry AV, Phaneuf PV, Poudel S, Palsson BO

2020
Directed Metabolic Pathway Evolution Enables Functional Pterin-Dependent Aromatic-Amino-Acid Hydroxylation in Escherichia coli

Luo H, Yang L, Kim SH, Wulff T, Feist AM, Herrgard M, Palsson BØ

2020
Redefining fundamental concepts of transcription initiation in bacteria

Mejía-Almonte C, Busby SJW, Wade JT, et al.

2020
Elucidation of Regulatory Modes for Five Two-Component Systems in Escherichia coli Reveals Novel Relationships

Choudhary KS, Kleinmanns JA, Decker K, Sastry AV, Gao Y, Szubin R, Seif Y, Palsson BO

2020
The y-ome defines the 35% of Escherichia coli genes that lack experimental evidence of function

S. Ghatak; Z.A. King; A. Sastry; B.O. Palsson

2019
Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism

Cheng C, O'Brien EJ, McCloskey D, Utrilla J, Olson C, LaCroix RA, Sandberg TE, Feist AM, Palsson BO, King ZA

2019
Expanding the uses of genome‐scale models with protein structures

Mih N and Palsson BO

2019
Pseudogene repair driven by selection pressure applied in experimental evolution.

A. Anand; C.A. Olson; L. Yang; A.V. Sastry; E. Catoiu; K.Sonal Choudhary; P.V. Phaneuf; T.E. Sandberg; S. Xu; Y. Hefner; R. Szubin; A.M. Feist; B.O. Palsson

2019
Synthetic Biology Tools for Novel Secondary Metabolite Discovery in Streptomyces

Lee N, Hwang S, Lee Y, Cho S, Palsson B, Cho BK

2019
The Escherichia coli transcriptome mostly consists of independently regulated modules

Sastry AV, Gao Y, Szubin R, Hefner Y, Xu S, Kim D, Choudhary KS, Yang L, King ZA, Palsson BO

2019
A computational knowledge-base elucidates the response of Staphylococcus aureus to different media types.

Y. Seif; J.M. Monk; N. Mih; H. Tsunemoto; S. Poudel; C. Zuniga; J. Broddrick; K. Zengler; B.O. Palsson

2019
Cellular responses to reactive oxygen species are predicted from molecular mechanisms

Yang L, Mih N, Anand A, Park JH, Tan J, Yurkovich JT, Monk JM, Lloyd CJ,
Sandberg TE, Seo SW, Kim D, Sastry AV, Phaneuf P, Gao Y, Broddrick JT, Chen K,
Heckmann D, Szubin R, Hefner Y, Feist AM, Palsson BO.

2019
Genome-scale model of metabolism and gene expression provides a multi-scale description of acid stress responses in Escherichia coli

Du B, Yang L, Lloyd CJ, Fang X, Palsson BO

2019
Metabolic Systems Analysis of Shock-Induced Endotheliopathy (SHINE) in Trauma: A New Research Paradigm

Henriksen HH, McGarrity S, SigurÐardóttir RS, Nemkov T, D'Alessandro A, Palsson BO, Stensballe J, Wade CE, Rolfsson Ó, Johansson PI

2019
BiGG Models 2020: multi-strain genome-scale models and expansion across the phylogenetic tree

Norsigian CJ, Pusarla N, McConn JL, Yurkovich JT, Dräger A, Palsson BO, King Z

2019
Comparative Genome-Scale Metabolic Modeling of Metallo-Beta-Lactamase-Producing Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates

Norsigian CJ, Attia H, Szubin R, Yassin AS, Palsson BØ, Aziz RK, Monk JM

2019