Dynamic simulation of the human red blood cell metabolic network.

Title Dynamic simulation of the human red blood cell metabolic network.
Year of Publication 2001
Authors N. Jamshidi; J.S. Edwards; T. Fahland; G.M. Church; B.Ø. Palsson
Journal PLoS Comput Biol
Abstract We have developed a Mathematica application package to perform dynamic simulations of the red blood cell (RBC) metabolic network. The package relies on, and integrates, many years of mathematical modeling and biochemical work on red blood cell metabolism. The extensive data regarding the red blood cell metabolic network and the previous kinetic analysis of all the individual components makes the human RBC an ideal 'model' system for mathematical metabolic models. The Mathematica package can be used to understand the dynamics and regulatory characteristics of the red blood cell.
URL PubMed