Project Scientist
My research involves developing computational approaches to studying biochemical networks. Applications of interest include:
- elucidating the dynamic structure of metabolic networks
- the functional interpretation of the metabolome
- impact of thermodynamics in biochemical network evolution
- computational metabolic engineering
- improved incorporation of fluxomic data into constraint-based models
- understanding objective functions and constraints relevant to modeling mammalian and multi-cellular metabolism
Education
2015, Ph.D. Bioengineering, University of California - San Diego, La Jolla, California
2008, B.S. Biomedical Engineering, University of Virginia, Charlottesville, Virginia
Select publications:
Zielinski, D.C. et. al., Systems biology analysis of drivers underlying hallmarks of cancer cell metabolism., Scientific Reports 25;7:41241. (2017).
Zielinski, D.C. et. al., Pharmacogenomic and clinical data link non-pharmacokinetic metabolic dysregulation to drug side effect pathogenesis., Nature Communications 9;6:7101. (2015).
Google Scholar for full list of publications.
Contact Information
Email Address: dczielin@ucsd.edu
Mailing Address: 9500 Gilman Drive Mail Code 0412 La Jolla, CA 92093-0412