I am a fifth year doctoral candidate in the Bioinformatics and Systems Biology graduate program at the University of California, San Diego.
My thesis is titled: "Optimality principles and tradeoffs in the evolution and regulation of Escherichia coli".
I am a fifth-year Bioengineering graduate student in the Palsson lab. My research is focused on metabolic engineering of E. coli to produce amino acids and other chemicals, and updating our genome scale E. coli reconstruction by filling in gaps using computational and experimental methods. I graduated from the University of Washington with a B.S. in Bioengineering in 2006.
Systems biology research accomplishments:
4th year Graduate Student
Program in Bioinformatics
My research currently focuses on modeling transcriptional regulatory networks and studying adaptive evolution in E. coli through the analysis and integration of so-called 'omics data sets. When not in the lab you can find me out and about enjoying San Diego with my better half (Kerri), seeking athletic glory through pickup soccer, rugby, and intramurals, or cheering wicked hard for the Sawx, B's, C's, and Pat's.
University of California, San Diego
I am finishing my sixth year as a graduate student in the Bioinformatics and Systems Biology Program. My research interests focus on Monte Carlo Sampling in Systems Biology. I defended my thesis on July 22nd, 2010 and am finishing a few manuscripts.
Email Address: jschelle-AT-ucsd.edu
Mailing Address: 9500 Gilman Drive Mail Code 0412 La Jolla, CA 92093-0412
This page is maintained by Daniel Zielinski.
Email Address: vasiliy.portnoy@gmail.com
Phone: (858) 822-1168
Mailing Address: 9500 Gilman Drive Mail Code 0412 La Jolla, CA 92093-0412
(Margaret) Kenyon Applebee is a fifth-year graduate student in the Palsson lab, from the Department of Chemistry & Biochemistry at UCSD. Her graduate work is focused on understanding the selection and function of mutations E. coli acquires while adaptively evolving to grow on challenging substrates. She has a BS in Biochemistry from the University of Illinois, Urbana-Champaign.
Email Address: mapplebe-at-chem.ucsd.edu
Phone: (858)822-1144
Scott is a fifth-year bioengineering graduate student working on the reconstruction and analysis of various biochemical reaction networks. His principal interests are applying systems biology methods to better understand human health and disease and different phenotypes of microorganisms, with applications in metabolic engineering.
Email Address: sabecker@ucsd.edu
Phone: (858)822-3180
Mailing Address: 9500 Gilman Drive, Mail Code 0412, La Jolla, CA 92093-0412
I am a Biochemistry PhD student. My research interests are adaptive evolution of bacteria, antibiotic resistance, systems biology, synthetic biology and bioengineering. There have been three aspects to my graduate research:
I'm a fourth year bioinformatic graduate student. I have reconstructed and characterized a metabolic model for the human cardiac mitochondria and core models for cardiomyocyte and hepatocyte. I have also developed an optimization-based framework to calculate reaction fluxes based on carbon tracer data (isotopomer data). Currently, I am carrying out 13C tracer experiments with normal and diseased fibroblasts to study cellular metabolic responses to changes in culture medium composition.
2002-present
