|Title||Genome-scale reconstruction of the sigma factor network in Escherichia coli: topology and functional states.|
|Publication Type||Journal Article|
|Year of Publication||2014|
|Authors||Cho B-K, Kim D, Knight EM, Zengler K, Palsson BO|
|PubMed Date||2014 Jan 24|
BACKGROUND: At the beginning of the transcription process, the RNAP core enzyme requires a sigma-factor to recognize the genomic location where the process initiates. Although the critical role of sigma-factors has been long appreciated and characterized for many individual promoters, we do not yet have a genome-scale assessment of their function.
|Alternate Journal||BMC Biol.|
Genome-scale reconstruction of the sigma factor network in Escherichia coli: topology and functional states.