|Title||Characterizing acetogenic metabolism using a genome-scale metabolic reconstruction of Clostridium ljungdahlii.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Nagarajan H, Sahin M, Nogales J, Latif H, Lovley DR, Ebrahim A, Zengler K|
|Journal||Microb Cell Fact|
BACKGROUND: The metabolic capabilities of acetogens to ferment a wide range of sugars, to grow autotrophically on H2/CO2, and more importantly on synthesis gas (H2/CO/CO2) make them very attractive candidates as production hosts for biofuels and biocommodities. Acetogenic metabolism is considered one of the earliest modes of bacterial metabolism. A thorough understanding of various factors governing the metabolism, in particular energy conservation mechanisms, is critical for metabolic engineering of acetogens for targeted production of desired chemicals.
|Alternate Journal||Microb. Cell Fact.|
Characterizing acetogenic metabolism using a genome-scale metabolic reconstruction of Clostridium ljungdahlii.