|Title||GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data.|
|Publication Type||Journal Article|
|Year of Publication||2013|
|Authors||Schmidt BJ, Ebrahim A, Metz TO, Adkins JN, Palsson BØ, Hyduke DR|
|PubMed Date||2013 Sep 14|
MOTIVATION: Genome-scale metabolic models have been used extensively to investigate alterations in cellular metabolism. The accuracy of these models to represent cellular metabolism in specific conditions has been improved by constraining the model with omics data sources. However, few practical methods for integrating metabolomics data with other omics data sources into genome-scale models of metabolism have been developed.
GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data.