|Title||Expa: a program for calculating extreme pathways in biochemical reaction networks.|
|Publication Type||Journal Article|
|Year of Publication||2005|
|Authors||Bell SL, Palsson BØ|
|Journal||Bioinformatics (Oxford, England)|
|PubMed Date||2005 Apr 15|
|Keywords||Animals, Biochemistry, Cell Physiological Phenomena, Energy Metabolism, Gene Expression Regulation, Humans, Proteome, Signal Transduction, Software|
The set of extreme pathways, a generating set for all possible steady-state flux maps in a biochemical reaction network, can be computed from the stoichiometric matrix, an incidence-like matrix reflecting the network topology. Here, we describe the implementation of a well-known algorithm to compute these pathways and give a summary of the features of the available software. AVAILABILITY: The C-code, along with a Windows executable and sample network reaction files, are available at http://systemsbiology.ucsd.edu CONTACT: firstname.lastname@example.org.