Nathan E. Lewis
 
 
Palsson Lab
Briggs Lab
Plant Sys Bio
 
   
 
About me I am currently a second year Bioengineering graduate student (spec. Bioinformatics) and an NSF IGERT plant systems biology fellow. My research interests include the use of in silico models of metabolism and transcriptional regulation for probing into disease states of tissue, chloroplast function (in conjunction with the lab of Dr. Steve Briggs), and elucidating transcriptional regulatory rules. In my free time I love cracking open science textbooks for leisure reading, hiking and biking, snorkeling in the La Jolla cove, and just spending time with my wife Maria and our daughter Anabelle.
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Current Research Computational Analysis of Arabidopsis Chloroplast Metabolism

Recently there has been an increased interest in both the computational analysis biological systems and the production of alternative energy sources. My research ties these areas together through a computational analysis of metabolism in chloroplasts and the experimental validation of computed predictions in order to better understand photosynthetic potential of Arabidopsis thaliana. My work with the Briggs lab allows me employ proteomic data into the modeling framework, allowing for more rapid model generation and prediction of pathway activation.
Publications, Posters, and Talks Publications: UCSD
  • Lewis NE, Jamshidi N, Thiele I, Palsson BO. Metabolic Systems Biology. Chapter in the Encyclopedia of Complexity and Systems Science. In press.
  • Lewis NE, Palsson BO. Gene Expression Profiling and the Elucidation of Metabolic and Regulatory Networks in Escherichia coli K-12. In preparation.
    • Posters and Talks: UCSD
  • Lewis NE, Cheng J, Patel N, Messersmith MP, Lewis RA, Palsson BO. Modeling the neurochemistry of Alzheimer's disease: a constraints-based approach. Talk at UCSD Interfaces Research Symposium 2008. Semi-finalist in abstract contest, and chosen as 1st place talk.
  • Lewis NE, Jobe T, Goswami S, Qutubuddin A, Briggs S, Palsson BO. Systems biology of the Arabidopsis chloroplast. Poster at IGERT 2008, Washington DC.
  • Lewis NE, Cheng J, Messersmith MP, Lewis RA, Palsson BO. Multi-compartment models of brain metabolism provides insight into theories in neurochemistry. Talk and poster at Experimental Biology 2008.
  • Lewis NE, Cheng J, Messersmith MP, Palsson BO. Talk at the 2008 All-grad research symposium.
    • Publications: BYU
  • Lewis NE, et al. Comparison of Sample Preparation Methods for Serum Proteome Biomarker Discovery. In preparation.
  • Merrell K, et al. Analysis of Low-Abundance, Low-Molecular-Weight Serum Proteins Using Mass Spectrometry. Journal of Biomolecular Techniques, 15, 238.

    Posters and Talks: BYU
  • Lewis NE, et al. Comparison of Sample Preparation Methods for Serum Proteome Biomarker Discovery. Presentation at the Conference for the Association of Biomolecular Resource Facilities 2006, Long Beach, CA. Semi-finalist in the poster contest.
  • Lewis NE, et al. Methods in Analysis of the Blood Serum Proteome: Preparation for biomarker discovery. Presentation at the BYU Spring Research Conference, March 2005.
  • Lewis NE, et al. A survey of serum treatments for biomarker discovery. Poster presented at the NIH, Aug 2004.
  • Merrell K, et al. Analysis of Low-Abundance Serum Proteins Using Mass Spectrometry. Presentation at the Conference for the Association of Biomolecular Resource Facilities. 2004, Portland, OR. Won the poster contest.
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    • Education 2006-present
    Ph.D. Bioengineering spec. Bioinformatics
    Univ of California, San Diego

    2008
    M.S. Bioengineering
    Univ of California, San Diego

    1998-2006
    B.S. Biochemistry, cum laude
    Brigham Young University

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    Contact Information

    Email Address

    n1lewis@my school name.edu

    Phone

    (858) 822-1144

    Mailing Address

    9500 Gilman Drive
    Mail Code 0412
    La Jolla, CA 92093-0412
    		 
     

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